Connote Healthcare Private Limited

Enalapril 5mg Tablets are an angiotensin-converting enzyme (ACE) inhibitor commonly prescribed to treat high blood pressure (hypertension) and heart failure. Enalapril works by blocking the enzyme that converts angiotensin I to angiotensin II, a hormone that causes blood vessels to constrict. By inhibiting this enzyme, Enalapril helps relax and widen the blood vessels, lowering blood pressure and reducing the strain on the heart. It is also used to improve survival after a heart attack and to protect the kidneys in people with diabetes or chronic kidney disease

Enalapril 10mg Tablets are an angiotensin-converting enzyme (ACE) inhibitor commonly used to treat high blood pressure (hypertension) and heart failure. Enalapril works by blocking the enzyme that converts angiotensin I to angiotensin II, a substance that causes blood vessels to constrict. By inhibiting this conversion, Enalapril helps relax blood vessels, lowering blood pressure and reducing the workload on the heart. It is also used to improve survival rates following a heart attack and to protect kidney function in individuals with diabetes or chronic kidney disease.

Enalapril 20mg Tablets are an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure (hypertension) and heart failure. Enalapril works by blocking the enzyme that converts angiotensin I to angiotensin II, a substance that narrows blood vessels. By inhibiting this conversion, Enalapril helps to relax and widen blood vessels, which lowers blood pressure and reduces the strain on the heart. It is also prescribed to help improve survival after a heart attack and to protect the kidneys in patients with diabetes or chronic kidney disease.

Captopril 50 mg tablets are an oral medication belonging to the class of drugs known as Angiotensin-Converting Enzyme (ACE) inhibitors. It is primarily used to treat high blood pressure (hypertension), heart failure, and left ventricular dysfunction after a heart attack. This specific dosage (50 mg) is a common therapeutic strength for these conditions.

 

Key Features:

• Antihypertensive: Effectively lowers high blood pressure, helping to reduce the risk of stroke and heart attack.
• Heart Failure Management: Improves symptoms and survival in patients with heart failure.
• Cardioprotective: Beneficial after a heart attack to improve heart function and prevent further damage.
• Renal Protective: Can help protect the kidneys in certain conditions, particularly in diabetic nephropathy (kidney disease due to diabetes).
• Oral Administration: Convenient tablet form for regular use.
• Quality Assured: Manufactured in WHO-GMP certified facilities.

Captopril 25 mg tablets are an oral medication belonging to the class of drugs known as Angiotensin-Converting Enzyme (ACE) inhibitors. It is primarily used to treat high blood pressure (hypertension), heart failure, and left ventricular dysfunction after a heart attack. This specific dosage (25 mg) is a common therapeutic strength for these conditions.

 

Key Features:

• Antihypertensive: Effectively lowers high blood pressure, helping to reduce the risk of stroke and heart attack.
• Heart Failure Management: Improves symptoms and survival in patients with heart failure.
• Cardioprotective: Beneficial after a heart attack to improve heart function and prevent further damage.
• Renal Protective: Can help protect the kidneys in certain conditions, particularly in diabetic nephropathy (kidney disease due to diabetes).
• Oral Administration: Convenient tablet form for regular use.
• Quality Assured: Manufactured in WHO-GMP certified facilities.

Amlodipine Besylate Tablet 5 mg is a widely prescribed medication, functioning as a dihydropyridine calcium channel blocker, and is a cornerstone in the long-term management of various cardiovascular conditions. Each tablet contains 10 milligrams of amlodipine (as amlodipine besylate), a powerful agent that works by inhibiting the influx of calcium ions into the smooth muscle cells of the heart and blood vessel walls. This selective action leads to the relaxation and widening of blood vessels (vasodilation), which in turn reduces peripheral vascular resistance, effectively lowering blood pressure and improving blood flow to the heart. This makes Amlodipine Besylate 10 mg highly effective for treating hypertension (high blood pressure) in adults and children aged 6 years and older, both as monotherapy or in combination with other antihypertensive agents. Furthermore, it is a crucial treatment for various forms of angina pectoris (chest pain), including chronic stable angina and vasospastic angina (Prinzmetal's or variant angina), by increasing oxygen supply to the heart muscle. It is also indicated for patients with angiographically documented coronary artery disease to reduce the risk of hospitalization for angina and the need for coronary revascularization procedures.

Amlodipine Besylate 10 mg is typically taken once daily, ensuring consistent medication levels in the bloodstream due to its long half-life, which contributes to its prolonged efficacy and improved patient adherence. The tablet should be swallowed whole with water, irrespective of food. While generally well-tolerated, common side effects can include swelling of the ankles or feet (edema), headache, dizziness, flushing, fatigue, and palpitations. Less common but serious side effects warranting immediate medical attention include severe low blood pressure, worsening chest pain (especially when initiating therapy or increasing dosage), or signs of liver problems (e.g., yellowing of skin or eyes).

Losartan Potassium 50mg Tablets are an angiotensin II receptor blocker (ARB) used primarily to treat high blood pressure (hypertension) and to help protect the kidneys in people with type 2 diabetes and kidney disease. Losartan works by blocking the action of a substance in the body called angiotensin II, which normally narrows blood vessels and raises blood pressure. By blocking this substance, Losartan helps relax blood vessels, lower blood pressure, and reduce the risk of stroke and heart attack.

• Apixaban 2.5 mg Tablet is an oral anticoagulant used to prevent and treat blood clots in various clinical conditions, including atrial fibrillation, deep vein thrombosis (DVT), and pulmonary embolism (PE). Apixaban belongs to a class of medications known as direct oral anticoagulants (DOACs), which inhibit Factor Xa, a key enzyme in the clotting process. By selectively blocking Factor Xa, Apixaban reduces the formation of thrombin, thereby decreasing the likelihood of clot formation.
• This 2.5 mg dosage is commonly prescribed for long-term management and prevention of thromboembolic events, providing a safer and more convenient alternative to traditional anticoagulants such as warfarin, with no requirement for regular blood monitoring.
• Key Features:
• Apixaban 2.5 mg – Direct inhibition of Factor Xa for effective blood clot prevention
• Used in the prevention and treatment of DVT, PE, and stroke prevention in atrial fibrillation
• No routine INR monitoring required
• Proven efficacy and safety profile in clinical trials
• Once or twice daily oral administration, depending on medical condition
• Manufactured in WHO-GMP certified facilities
• Composition (per tablet):
• Apixaban: 2.5 mg
• Excipients: q.s.
• Tablet form: Round, film-coated
• Indications:
• Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation
• Treatment of DVT and PE
• Prevention of recurrent DVT and PE
• Prevention of thromboembolic events following orthopedic surgery (e.g., hip or knee replacement)

Additional Information:

• Production Capacity: unlimited
• Delivery Time: 4-6 weeks

Nebivolol 5 mg tablets are an oral medication belonging to the class of beta-blockers, specifically a highly selective beta-1 adrenergic receptor antagonist. It is primarily used to treat high blood pressure (hypertension) in adults, either alone or in combination with other medicines. This lower strength is often prescribed for initial dosing, particularly in elderly patients or those with kidney impairment. It is also used to manage mild to moderate chronic heart failure in patients aged 70 years or over, in addition to other prescribed therapies.

Key Features:

• Selective Beta-Blocker: Primarily targets the heart's beta-1 receptors, leading to a slower heart rate and reduced blood pressure.
• Antihypertensive: Effectively lowers high blood pressure, reducing the risk of complications like stroke, heart attack, and kidney failure.
• Heart Failure Management: Used as an add-on therapy for chronic heart failure in elderly patients.
• Oral Administration: Convenient tablet form, typically taken once daily.
• Quality Assured: Manufactured in WHO-GMP certified facilities.

• Apixaban 5 mg Tablet is an oral anticoagulant used to prevent and treat blood clots in various clinical conditions, including atrial fibrillation, deep vein thrombosis (DVT), and pulmonary embolism (PE). Apixaban belongs to a class of medications known as direct oral anticoagulants (DOACs), which inhibit Factor Xa, a key enzyme in the clotting process. By selectively blocking Factor Xa, Apixaban reduces the formation of thrombin, thereby decreasing the likelihood of clot formation.
• This 5 mg dosage is commonly prescribed for long-term management and prevention of thromboembolic events, providing a safer and more convenient alternative to traditional anticoagulants such as warfarin, with no requirement for regular blood monitoring.
• Key Features:
• Apixaban 5 mg – Direct inhibition of Factor Xa for effective blood clot prevention
• Used in the prevention and treatment of DVT, PE, and stroke prevention in atrial fibrillation
• No routine INR monitoring required
• Proven efficacy and safety profile in clinical trials
• Once or twice daily oral administration, depending on medical condition
• Manufactured in WHO-GMP certified facilities
• Composition (per tablet):
• Apixaban: 5 mg
• Excipients: q.s.
• Tablet form: Round, film-coated
• Indications:
• Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation
• Treatment of DVT and PE
• Prevention of recurrent DVT and PE
• Prevention of thromboembolic events following orthopedic surgery (e.g., hip or knee replacement)

Additional Information:

• Production Capacity: unlimited
• Delivery Time: 4-6 weeks

Diltiazem Hydrochloride 30 mg tablets are an oral medication belonging to the calcium channel blocker (CCB) class. It is primarily used to treat high blood pressure (hypertension), manage angina pectoris (chest pain), and control certain heart rhythm disorders (arrhythmias). This lower dose is often used for initial titration or for conditions requiring a milder effect.

Diltiazem works by blocking calcium from entering heart and blood vessel cells, leading to relaxation and widening of blood vessels, a slower heart rate, reduced force of heart muscle contraction, and improved blood flow to the heart.

Key Features:

• Calcium Channel Blocker: A well-established class of cardiovascular medications.
• Multi-Purpose: Effective for hypertension, angina, and certain arrhythmias.
• Reduces Heart's Workload: Lowers heart rate, relaxes blood vessels, and decreases contractility.
• Oral Administration: Convenient tablet form for regular use.
• Quality Assured: Manufactured in WHO-GMP certified facilities.

Composition (per tablet):

• Diltiazem Hydrochloride IP: 30 mg
• Excipients: q.s.

Indications:

• Essential Hypertension: For the treatment of high blood pressure in adults.
• Chronic Stable Angina Pectoris: For the prevention and management of chest pain due to coronary artery disease.
• Prinzmetal's (Variant) Angina: For treating this specific type of angina.
• Atrial Fibrillation/Flutter: For controlling ventricular rate in patients with chronic atrial fibrillation or atrial flutter.

Losartan Potassium 25 mg tablets are an oral medication classified as an Angiotensin II Receptor Blocker (ARB), primarily prescribed to treat high blood pressure (hypertension) in adults. This lower strength is often used to initiate treatment or for patients requiring a milder reduction in blood pressure.

Beyond hypertension, Losartan 25 mg is also indicated to protect the kidneys from damage in patients with Type 2 diabetes and hypertension (diabetic nephropathy) and to lower the risk of stroke in patients with high blood pressure and an enlarged heart (left ventricular hypertrophy). It is frequently used when a reduction in blood pressure is needed to prevent future cardiovascular events like heart attacks and strokes.

Propranolol Hydrochloride 80 mg tablets are an oral medication belonging to the class of drugs known as beta-blockers (specifically, non-selective beta-adrenergic receptor antagonists). It is widely used to treat a variety of cardiovascular conditions and other disorders, including high blood pressure, angina (chest pain), certain irregular heart rhythms (arrhythmias), anxiety, essential tremor, and for the prevention of migraine headaches.

 

Key Features:

• Multi-Purpose Beta-Blocker: Effective across a broad range of conditions affecting the heart, nervous system, and other body functions.
• Reduces Heart Rate and Blood Pressure: Helps the heart beat slower and with less force, which lowers blood pressure and reduces the heart's workload.
• Anti-Anginal: Prevents and reduces the frequency and severity of angina attacks.
• Anti-Arrhythmic: Helps stabilize abnormal heart rhythms.
• Migraine Prophylaxis: Can prevent the onset of migraine headaches.
• Anxiety Symptom Relief: Helps manage physical symptoms of anxiety like racing heart and trembling.
• Oral Administration: Convenient tablet form for regular use.
• Quality Assured: Manufactured in WHO-GMP certified facilities.

 

Glimepiride 4 mg tablets are an oral antidiabetic medication belonging to the sulfonylurea class. It is used for the management of Type 2 Diabetes Mellitus in adults. This lower strength is particularly useful for initiating therapy, for patients requiring a milder dose to achieve glycemic control, or as part of a combination regimen.

 

Mechanism of Action: Glimepiride primarily works by stimulating the beta cells in the pancreas to release more insulin. It achieves this by binding to specific receptors on these cells, which leads to the closure of ATP-sensitive potassium channels. This triggers a cascade of events that cause the pancreatic beta cells to depolarize and release insulin. The increased insulin in the bloodstream helps to lower blood glucose by facilitating glucose uptake into cells and reducing hepatic glucose output. Glimepiride also exhibits some extrapancreatic effects, potentially improving insulin sensitivity.

 

Key Features:

• Insulin Secretagogue: Directly stimulates the pancreas to increase insulin secretion.
• Effective Blood Glucose Control: Helps lower both fasting and post-meal blood sugar levels.
• Flexible Dosing: Available in various strengths, allowing for dose titration based on individual patient needs.
• Once-Daily Dosing: Can be taken once daily with breakfast or the first main meal.
• Quality Assured: Manufactured in WHO-GMP certified facilities.

Composition (per tablet):

• Glimepiride IP: 0.5 mg
• Excipients: q.s.

Indications:

• Type 2 Diabetes Mellitus: Indicated as an adjunct to diet and exercise in adult patients to improve glycemic control. It can be used as monotherapy (especially in newly diagnosed patients or those sensitive to higher doses) or in combination with other oral antidiabetic agents (e.g., Metformin) or insulin.

Hydrochlorothiazide 50 mg Tablets are a powerful thiazide diuretic, commonly known as a "water pill." Each uncoated tablet contains Hydrochlorothiazide 50 mg. This medication is widely used for two primary purposes: managing hypertension (high blood pressure) and treating edema (fluid retention).

For high blood pressure, Hydrochlorothiazide works by helping your body get rid of excess sodium and water through the kidneys, which in turn lowers blood pressure and reduces the risk of serious cardiovascular events like stroke, heart attack, and kidney damage. When it comes to fluid retention, it effectively treats swelling caused by various conditions such as heart failure, kidney disorders, liver disease, or even certain medications.

This medication should always be taken as directed by a registered medical practitioner. While the 50 mg strength is often used for more persistent high blood pressure or significant edema, it's typically taken once daily, preferably in the morning to avoid nighttime urination.

Our Hydrochlorothiazide 50 mg Tablets are available in standard strip packaging (e.g., 10 tablets per strip), with bulk packaging options available upon request. We ensure all products are manufactured under strict quality control standards, adhering to cGMP (current Good Manufacturing Practices) and all Indian pharmaceutical regulations. Every batch undergoes rigorous testing for purity, potency, and stability.

For our IndiaMART buyers, we offer competitive bulk pricing and ensure a reliable supply chain with efficient, pan-India delivery. We are committed to providing assured quality from reputable manufacturers. We also welcome inquiries regarding private labeling or third-party manufacturing services. Please contact us to discuss our Minimum Order Quantity (MOQ) and how we can meet your specific needs. This is a prescription-only medication for ethical medical use.

Nicorandil 5 mg tablets are an oral medication for preventing and treating chest pain (angina pectoris). This unique drug works by a dual mechanism: activating potassium channels and donating nitric oxide. Both actions relax and widen blood vessels, significantly increasing blood and oxygen supply to the heart while reducing its workload. It's typically prescribed when other angina medications aren't suitable or effective, offering a crucial option to alleviate and prevent angina episodes.

Clopidogrel Tablet USP 75mg is an antiplatelet medication, also known as a blood thinner, that is widely prescribed to prevent the formation of harmful blood clots in blood vessels. Adhering to United States Pharmacopeia (USP) standards, this tablet is crucial for individuals at high risk of cardiovascular events. It functions by irreversibly inhibiting the P2Y12 receptor on platelets, thereby preventing them from clumping together and forming clots that can lead to serious conditions like heart attacks, strokes, or severe chest pain (unstable angina). This medication is commonly indicated for patients with a history of recent myocardial infarction (heart attack), recent stroke, or established peripheral arterial disease. It is also often used in combination with aspirin (dual antiplatelet therapy) following percutaneous coronary intervention (PCI), such as stent placement, to reduce the risk of stent thrombosis and other adverse cardiovascular events. As a prescription-only medication, strict adherence to medical guidance and continuous monitoring are essential due to the increased risk of bleeding. For suppliers and buyers on IndiaMART, ensuring that Clopidogrel Tablet USP 75mg products meet all quality, safety, and regulatory guidelines set by the Central Drugs Standard Control Organisation (CDSCO) in India is paramount for patient well-being and market compliance.

Losartan Potassium & Hydrochlorothiazide Tablets (50 mg + 12.5 mg) are a combination medication used to manage high blood pressure (hypertension). This dual-action formulation combines:

• Losartan Potassium (50 mg): An Angiotensin II receptor blocker (ARB) that relaxes blood vessels by inhibiting the effects of angiotensin II, a substance that narrows blood vessels.

• Hydrochlorothiazide (12.5 mg): A thiazide diuretic that helps reduce fluid retention by increasing urine output, thereby lowering blood pressure.

Indications:

• Management of essential hypertension in adults.

• Reduction of the risk of stroke in patients with left ventricular hypertrophy.

Dosage:

• The usual starting and maintenance dose is one tablet of Losartan Potassium & Hydrochlorothiazide (50 mg + 12.5 mg) once daily.

• For patients who do not respond adequately, the dosage may be increased to one tablet of Losartan Potassium & Hydrochlorothiazide (100 mg + 25 mg) once daily.

Precautions:

• Not recommended for use in pregnant women, especially during the second and third trimesters.

• Caution is advised in patients with renal or hepatic impairment.

• Regular monitoring of blood pressure, kidney function, and electrolytes is recommended during treatment.

Side Effects:

• Common side effects may include dizziness, lightheadedness, or fainting, especially when standing up quickly.

• Less common side effects may include headache, fatigue, nausea, and muscle cramps.

Storage:

• Store at room temperature, away from moisture and heat.

• Keep out of reach of children.

Hydrochlorothiazide Tablets BP 25 mg are a thiazide diuretic commonly prescribed to manage hypertension (high blood pressure) and edema (fluid retention) associated with conditions such as heart failure, liver cirrhosis, and kidney disorders. Each tablet contains 25 mg of Hydrochlorothiazide as the active ingredient.

Key Benefits:

• Blood Pressure Management: Helps lower high blood pressure, reducing the risk of strokes, heart attacks, and kidney problems.

• Edema Reduction: Aids in the treatment of edema by removing excess fluid from the body, providing relief from swelling and discomfort.

• Heart Health: Reduces the workload on the heart and arteries, contributing to overall cardiovascular health.

• Kidney Function: Helps maintain proper kidney function by preventing the formation of kidney stones and managing conditions like nephrotic syndrome.

Usage Instructions:

• Dosage: As prescribed by a healthcare professional.

• Administration: Swallow the tablet whole with a glass of water; do not chew or crush.

• Storage: Store in a cool, dry place away from direct sunlight and moisture.

Precautions:

• Consult a healthcare provider before starting treatment, especially if you have a history of kidney disease, liver disease, or electrolyte imbalances.

• Regular monitoring of blood pressure and kidney function is recommended during treatment.

• Avoid sudden position changes to minimize dizziness.

Digoxin Tablets BP 0.125 mg are a highly specialized cardiac glycoside medication, conforming to British Pharmacopoeia standards, primarily prescribed for the management of certain heart conditions. This potent medication is widely utilized in India for its efficacy in improving the pumping strength of the heart in patients suffering from mild to moderate chronic heart failure, where it helps alleviate symptoms like swelling and breathlessness. Additionally, it plays a crucial role in regulating abnormal heart rhythms, such as chronic atrial fibrillation and atrial flutter, by controlling the ventricular rate and promoting a more stable heartbeat. Given its narrow therapeutic index, accurate dosage and close medical supervision, including regular blood tests and ECGs, are paramount to ensure patient safety and optimize therapeutic outcomes.

• Hydrochlorothiazide 25mg Tablets are a prescription diuretic medication used to treat high blood pressure (hypertension), fluid retention (edema) due to congestive heart failure, liver cirrhosis, or kidney disorders. These tablets help reduce excess fluid in the body by increasing urine output, thereby lowering blood pressure and swelling.
• Key Features:

• Each tablet contains 25 mg of Hydrochlorothiazide

• Diuretic and antihypertensive agent

• Helps manage fluid retention and high blood pressure

• Improves cardiovascular health when used as prescribed

• Available in strip or bulk packaging

• Manufactured under WHO-GMP certified facilities

• Usage/Application:

• Treatment of hypertension

• Management of edema associated with heart, liver, or kidney conditions

Additional Information:

• Production Capacity: Unlimited
• Delivery Time: 4-6 Weeks